Dominique cosmetics will close its flagship location in Dublin next year and shut down its flagship in Limerick in 2019.
It will continue to sell its fragrances and cosmetics at a store in the city but will cease to manufacture and sell its cosmetics and products, it said in a statement on Tuesday.
Dominique said in its statement that it was withdrawing its brand from the market as it did not feel the current environment was sustainable for the business.
Dominiqué said it had recently acquired a large quantity of chemicals and chemicals products.
It said it was taking all measures to maintain a safe and sustainable business and to ensure it does not impact on other businesses in the region.
Dominiques parent company, the Italian company CIE, has also announced that it is closing its flagship store in Dublin.
It announced the closure on Monday after a number of years of struggling sales and operating losses.
The company is seeking a buyer for its assets.